Smad5 抗体, ウサギポリクローナル抗体, Antigen Affinity Purified

レビューを送信する | リファレンスを送信する

マウス SMAD5 抗体製品情報

免疫原:	Recombinant Mouse SMAD5 protein (Catalog#50728-M20B)
Clone ID:
Ig タイプ:	Rabbit IgG
濃度:
エンドトキシン:
製剤:	0.2 μm filtered solution in PBS with 5% trehalose
調製:	Produced in rabbits immunized with purified, recombinant Mouse SMAD5 (rM SMAD5; Catalog#50728-M20B; P97454; Thr2-Ser465). SMAD5 specific IgG was purified by Mouse SMAD5 affinity chromatography.

マウス SMAD5 抗体使用ガイド

特異度:	Mouse SMAD5
アプリケーション:	ELISA, IHC-P ELISA: 0.1-0.2 μg/mL This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Mouse SMAD5. The detection limit for Mouse SMAD5 is approximately 0.00975 ng/well. IHC-P: 0.1-2 μg/mL
保存:	This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

マウス SMAD5 Antibody IHC Application Image

Smad5 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry

[クリックして画像を拡大]
Caption:
Immunochemical staining of mouse SMAD5 in mouse intestine with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections).

Other SMAD5 Antibody Products

Smad5 背景

SMAD5 is a member of the SMAD family. Members of this family mediate signal transduction by the TGF-beta/activin/BMP-2/4 cytokine superfamily from receptor Ser/Thr protein kinases at the cell surface to the nucleus. SMAD5 is involved in the TGF-beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. It is also involved in cell signalling and modulates signals of bone morphogenetic proteins (BMP's). The binding of ligands causes the oligomerization and phosphorylation of the SMAD5 protein. SMAD5 is a receptor regulated SMAD (R-SMAD) and is activated by bone morphogenetic protein type 1 receptor kinase.

マウス Smad5 参考文献

Vinayagam A. et al., 2011, Sci Signal. 4 (189): rs8.

Sangadala S. et al., 2007, J Biomol Struct Dyn. 25 (1): 11-23.

Riggins GJ. et al., 1996, Nat Genet. 13 (3): 347-9.

Proteins

Antibodies

ELISA Kits