Anti-Periostin Antibody

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Anti-Periostin Antibody (Rabbit Polyclonal 抗体) の製品情報

製品名
Anti-Periostin Antibody
検証済のアプリケーション
ELISA,IHC-P
交差反応
Reacts with: Mouse
特異性
Mouse Periostin
免疫原
Recombinant Mouse Periostin / POSTN protein (Catalog#50450-M08H)
調製
Produced in rabbits immunized with purified, recombinant Mouse Periostin / POSTN (rM Periostin / POSTN; Catalog#50450-M08H; NP_056599.1; Met 1-Gln 811). Periostin / POSTN specific IgG was purified by Mouse Periostin / POSTN affinity chromatography.
ソース
Polyclonal Rabbit IgG
精製
Protein A & Antigen Affinity
緩衝液
0.2 μm filtered solution in PBS
標識物
Unconjugated
状態
Liquid
配送方法
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
保存条件
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-Periostin Antibody (Rabbit Polyclonal 抗体) 検証済のアプリケーション

アプリケーション 推奨希釈率/用量
ELISA 1:5000-1:10000
IHC-P 1:500-1:2000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-Periostin Antibody (Rabbit Polyclonal 抗体) の画像

Immunochemical staining of mouse POSTN in mouse stomach with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).

Anti-Periostin Antibody: 別名

Anti-A630052E07Rik Antibody; Anti-AI747096 Antibody; Anti-OSF-2 Antibody; Anti-Osf2 Antibody; Anti-peri Antibody; Anti-PLF Antibody; Anti-PN Antibody

Periostin 背景情報

Periostin ( POSTN ), also known as OSF2 (osteoblast specific factor 2), is a heterofunctional secreted extracellular matrix (ECM) protein comprised of four fasciclin domains that promotes cellular adhesion and movement, as well as collagen fibrillogenesis. Postn is expressed in unique growth centers during embryonic development where it facilitates epithelial-mesenchymal transition (EMT) of select cell populations undergoing reorganization. In the adult, Postn expression is specifically induced in areas of tissue injury or areas with ongoing cellular re-organization. In the adult heart Postn is induced in the ventricles following myocardial infarction, pressure overload stimulation, or generalized cardiomyopathy. Although the detailed function of Postn is still unclear, Postn-integrin interaction is thought to be involved in tumor development. Postn is frequently overexpressed in various types of human cancers, stimulating metastatic growth by promoting cancer cell survival, invasion and angiogenesis, and can be a useful marker to predict the behavior of cancer.
完全な名称
periostin, osteoblast specific factor
参考文献
  • Kudo,Y. et al., 2007, Histol Histopathol. 22 (10):1167-1174.
  • Li, J.S. et al., 2007, World J Gastroenterol. 13 (39): 5261-5266.
  • Oku, E. et al., 2008, Int J Hematol. 88 (1): 57-63.
  • Hamilton, D.W. et al., 2008, J Cell Commun Signal. 2(1-2):9-17.
  • Puglisi, F.J et al., 2008, Clin Pathol. 61 (4): 494-498.
  • Conway, S. J. et al., 2008, Curr Genomics. 9 (8): 548-555.

Standard Antibody Development Service

Rabbit MAb

Mouse MAb

Rabbit PAb

Fast Antibody Development Service

Mouse MAb

Rabbit PAb

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