All PDGFRB reagents are produced in house and quality controlled, including 16 PDGFRB Antibody, 1 PDGFRB ELISA, 39 PDGFRB Gene, 8 PDGFRB Lysate, 8 PDGFRB Protein, 2 PDGFRB qPCR. All PDGFRB reagents are ready to use.
Recombinant PDGFRB proteins are expressed by HEK293 Cells with fusion tags as C-human IgG1-Fc, C-human IgG1-Fc & His, C-His, C-cleavage.
PDGFRBantibodies are validated with different applications, which are FCM, IHC-P, ELISA, ELISA(Det), ELISA(Cap).
PDGFRBcDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each PDGFRB of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
PDGFRBELISA Kit are quality controlled by 8 internation QC standard which guarantee every ELISA Kit with high quality.
Expression host: HEK293 Cells
The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD140b, also known as PDGFRB, is a member of the CD system. CD140b is a cell surface tyrosine kinase receptor essencial for development interacting with the platelet-derived growth factors (PDGFs) which serves as mitogens for mesenchymal cells. CD140b can bind with platelet-derived growth factor (PDGF)-B, that are secreted by tumors and phosphorylation of PDGFR-β was correlated with depth of cancer invasion at statistically significant level.