ORC4: ORC4 Protein | ORC4 Antibody

ORC4 Gene family

ORC4 Protein

ORC4 protein function

Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3.

ORC4 protein sequence

This sequence information is just for reference only.From Uniport

  • Length
  • Mass (Da)

ORC4 Gene

ORC4 cDNA / gene is a gene with protein product which located on 2q23.1. The ORC4 gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, S.pombe, A.thaliana, rice, and frog. 246 organisms have orthologs with human gene ORC4.