Neurogenin-3 / NEUROG3 (タンパク質 | 抗体 | cDNA クローン | ELISA キット)

All Neurogenin-3 / NEUROG3 reagents are produced in house and quality controlled, including 1 Neurogenin-3 / NEUROG3 Antibody, 2 Neurogenin-3 / NEUROG3 Gene, 1 Neurogenin-3 / NEUROG3 qPCR. All Neurogenin-3 / NEUROG3 reagents are ready to use.

Neurogenin-3 / NEUROG3 の背景知識

NEUROG3 plays a central role in the development of both pancreatic islets and enteroendocrine cells. Homozygous hypomorphic missense mutations in NEUROG3 have been recently associated with a rare form of congenital malabsorptive diarrhea secondary to enteroendocrine cell dysgenesis.Neurogenin3 (NEUROG3) is a basic helix-loop-helix transcription factor required for development of the endocrine pancreas in mice. NEUROG3 is essential for endocrine pancreas development in humans and that as little as 1% NEUROG3 is sufficient for formation of pancreatic endocrine cells.