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NAALADL1 Antibody, Rabbit PAb, Antigen Affinity Purified

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Mouse NAALADL1 抗体製品情報
免疫原:Recombinant Mouse NAALADL1 protein (Catalog#50937-M07H)
Clone ID:
Ig タイプ:Rabbit IgG
濃度:
エンドトキシン:
製剤:0.2 μm filtered solution in PBS with 5% trehalose
調製:Produced in rabbits immunized with purified, recombinant Mouse NAALADL1 (rM NAALADL1; Catalog#50937-M07H; Q7M758; Pro29-Leu745). NAALADL1 specific IgG was purified by Mouse NAALADL1 affinity chromatography.
Mouse NAALADL1 抗体使用ガイド
特異度:Mouse NAALADL1
アプリケーション:ELISA, IHC-P

ELISA: 0.1-0.2 μg/mL

This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Mouse NAALADL1 . The detection limit for Mouse NAALADL1 is 0.00975 ng/well.

IHC-P: 0.1-2 μg/mL

保存:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Mouse NAALADL1 Antibody IHC Application Image
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Caption:
Immunochemical staining of mouse NAALADL1 in mouse brain with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections).
NAALADL1 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
Other NAALADL1 Antibody Products
NAALADL1 背景

N-acetylated-alpha-linked acidic dipeptidase-like protein, also known as NAALADL1, NAALADase L, and Ileal dipeptidylpeptidase, is a Single-pass type I I membrane protein and a member of the peptidase M28 family and M28B subfamily. NAALADase L is mainly expressed in the distal small intestine. It is also expressed in the spleen and testis and Weakly expressed in the brain, locating mainly to the brain stem, amygdala, thalamus and ventral striatum. NAALADase L is a chloride-activated, membrane bound, metallopeptidase that cleaves the endogenous neuropeptide N-acetyl-aspartyl-glutamate (NAAG). NAAG acts as a partial NMDA agonist as well as a full agonist at the presynaptic metabotropic glutamate receptor 3 (mGluR3), where it acts to reduce glutamate release. NAALADase L also exhibits a dipeptidyl-peptidase IV type activity. NAALADase inhibition may be a novel therapeutic approach to reduce or inhibit heightened aggressiveness, and possibly to treat aggressive behavior associated with psychiatric disorders.

Mouse NAALADL1 参考文献
  • Stauch BL. 1989, Neurosci Lett. 100 (1-3): 295-300.
  • Shneider BL. et al., 1997, J. Biol. Chem. 272: 31006-15.
  • Pangalos MN. et al., 1999, J. Biol. Chem. 274: 8470-83.
  • Thomas AG. et al., 1999, Brain Res. 843 (1-2): 48-52.
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    Size / Price
    カタログ: 50937-RP02-50
    定価:   (Save )
    価格:      [How to order]
    可用性In Stock
     配送方法
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