IL22 qPCR Primer Pairs, Mouse

Cat: MP201043
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IL22 qPCR Primer Pairs, Mouse General Information
Target Details
Species:
Mouse
Product Details
Oligo-Type:
qPCR Primers
Component:
1 vial of lyophilized qPCR primer mix (1 nmol each primer, sufficient for 200 numbers of 25 μl reactions).
QPCR Primer Description:
Verified forward and reverse primers for analyzing the quantitative expression of gene.
Application & Quality
Application:
SYBR® Green-based quantitative real-time PCR (qPCR).
Quality Control:
The primer mix has been verified to generate satisfactory qPCR data on Roche Applied-science LightCycler® 480 Ⅱ.
Storage & Shipping
Shipping:
Lyophilized qPCR primer mix is shipped at ambiente temperatura
Storage:
The lyophilized product is stable for one year from date of receipt when stored at -20℃. The suspended product is stable for six months from date of receipt when stored at -20℃.

***Sino biological qEASY qPCR primer pairs are used for SYBR Green-based real-time RT-PCR, The primers are designed by using SBI's proprietary primer design algorithm. Our primer collection covers the entire human genomes. It can be widely applied in the quantitative analysis of gene expression.***

Features and Advantages
Unique Primer Design
To avoid genomic DNA amplification, at least one primer is designed crosses the junction of exons according to the conserved region of a specific gene with all variants.
Strict Validation Process
Confirmed in positive organizations; screened the primer with high specificity and high sensitivity.
Uniform PCR conditions, Saving time and cost
~100% amplification curve, ensuring the accuracy of the RNA quantitative
IL22 qPCR Primer Pairs, Mouse Alternative Names
IL-22 qPCR Primer Pairs, Mouse;IL-22a qPCR Primer Pairs, Mouse;Iltif qPCR Primer Pairs, Mouse;ILTIFa qPCR Primer Pairs, Mouse
IL22 Background Information

IL22 is a member of a group of cytokines called the IL-10 family or IL-10 superfamily (including IL-19, IL-20, IL-24, and IL-26),  a class of potent mediators of cellular inflammatory responses. It shares use of IL-10R2 in cell signaling with other members of this family, IL-10, IL-26, IL-28A/B and IL-29. IL22 is produced by activated DC and T cells and initiates innate immune responses against bacterial pathogens especially in epithelial cells such as respiratory and gut epithelial cells. IL22 along with IL-17 is rapidly produced by splenic LTi-like cells and can be also produced by Th17 cells and likely plays a role in the coordinated response of both adaptive and innate immune systems.

IL22 biological activity is initiated by binding to a cell-surface complex composed of IL-22R1 and IL-10R2 receptor chains and further regulated by interactions with a soluble binding protein, IL-22BP, which shares sequence similarity with an extracellular region of IL-22R1 (sIL-22R1). IL22 and IL-10 receptor chains play a role in cellular targeting and signal transduction to selectively initiate and regulate immune responses. IL22 can contribute to immune disease through the stimulation of inflammatory responses, S100s and defensins. IL22 also promotes hepatocyte survival in the liver and epithelial cells in the lung and gut similar to IL-10. In some contexts, the pro-inflammatory versus tissue-protective functions of IL22 are regulated by the often co-expressed cytokine IL-17A.

Full Name
interleukin 22
References
  • Pestka S. et al., 2004, Annu Rev Immunol. 22: 929-79.
  • Xie MH. et al., 2000, J Biol Chem. 275 (40): 31335-9.
  • Jones BC. et al., 2008, Structure. 16 (9): 1333-44.
  • IL22 qPCR Primer Pairs, Rat, Related Products

    Product Name Catalog#(PDF)
    IL22 cDNA ORF Clone in Cloning Vector, Rat RG80463-G
    IL22 cDNA ORF Clone, Rat, untagged RG80463-UT
    IL22 Lentiviral cDNA ORF Clone, Rat, C-GFPSpark® tag RG80463-ACGLN
    IL22 cDNA ORF Clone, Rat, C-GFPSpark® tag RG80463-ACG
    IL22 cDNA ORF Clone, Rat, C-OFPSpark® tag RG80463-ACR
    IL22 cDNA ORF Clone, Rat, C-DDK (Flag®) tag RG80463-CF
    IL22 cDNA ORF Clone, Rat, N-DDK (Flag®) tag RG80463-NF
    IL22 cDNA ORF Clone, Rat, C-His tag RG80463-CH
    IL22 cDNA ORF Clone, Rat, N-His tag RG80463-NH
    IL22 cDNA ORF Clone, Rat, C-HA tag RG80463-CY
    IL22 cDNA ORF Clone, Rat, N-HA tag RG80463-NY
    IL22 cDNA ORF Clone, Rat, C-Myc tag RG80463-CM
    IL22 cDNA ORF Clone, Rat, N-Myc tag RG80463-NM

    IL22 qPCR Primer Pairs, Mouse, Related Products

    Product Name Catalog#(PDF)
    IL22 cDNA ORF Clone in Cloning Vector, Mouse MG51085-G
    IL22 cDNA ORF Clone, Mouse, untagged MG51085-UT
    IL22 cDNA ORF Clone, Mouse, C-GFPSpark® tag MG51085-ACG
    IL22 Lentiviral cDNA ORF Clone, Mouse, C-GFPSpark® tag MG51085-ACGLN
    IL22 cDNA ORF Clone, Mouse, C-OFPSpark® tag MG51085-ACR
    IL22 cDNA ORF Clone, Mouse, C-DDK (Flag®) tag MG51085-CF
    IL22 cDNA ORF Clone, Mouse, N-DDK (Flag®) tag MG51085-NF
    IL22 cDNA ORF Clone, Mouse, C-His tag MG51085-CH
    IL22 cDNA ORF Clone, Mouse, N-His tag MG51085-NH
    IL22 cDNA ORF Clone, Mouse, C-HA tag MG51085-CY
    IL22 cDNA ORF Clone, Mouse, N-HA tag MG51085-NY
    IL22 cDNA ORF Clone, Mouse, C-Myc tag MG51085-CM
    IL22 cDNA ORF Clone, Mouse, N-Myc tag MG51085-NM

    IL22 qPCR Primer Pairs, Human, Related Products

    Product Name Catalog#(PDF)
    IL22 cDNA ORF Clone, Human, untagged HG13059-UT
    IL22 Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag HG13059-ACGLN
    IL22 cDNA ORF Clone, Human, C-His tag HG13059-CH
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