All MMP19 reagents are produced in house and quality controlled, including 1 MMP19 Antibody, 1 MMP19 Gene, 1 MMP19 Protein. All MMP19 reagents are ready to use.
Recombinant MMP19 proteins are expressed by E. coli with fusion tags as Native.
MMP19antibodies are validated with different applications, which are ELISA.
MMP19cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each MMP19 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
MMP19, also known as RASI-1, is a member of the peptidase M10A family. It contains 4 hemopexin-like domains and is expressed in mammary gland, placenta, lung, pancreas, ovary, small intestine, spleen, thymus, prostate, testis colon, heart and blood vessel walls. It is a matrix metalloproteinase (MMP). Proteins of the MMP family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP19 may play a role in pathological processes participating in rheumatoid arthritis (RA)-associated joint tissue destruction. Autoantigen anti-MMP19 are frequent in RA patients.