クイック注文

MMP-16  Protein, Antibody, ELISA Kit, cDNA Clone

MMP-16 関連経路

MMP-16 関連製品

MMP-16 関連製品

Featured Reagent Products

MMP-16 サマリー & タンパク質情報

MMP-16 背景

補因子: Binds 1 zinc ion per subunit (By similarity).
Calcium (By similarity).
酵素調節: TIMP-2 shows little inhibitory activity compared to TIMP-1. TIMP-1 seems to have less binding affinity than TIMP-2 for the short isoform.
サブユニット構造: Interacts with CSPG4 through CSPG4 chondroitin sulfate glycosaminoglycan.
ドメイン: The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.
細胞内位置: Isoform Long: Cell membrane; Single-pass type I membrane protein; Extracellular side (Potential). Note=Localized at the cell surface of melanoma cells.
Isoform Short: Secreted, extracellular space, extracellular matrix. Cell surface. Note=Localized at the cell surface of melanoma cells.
組織特異性: Expressed in heart, brain, placenta, ovary and small intestine. Isoform Short is found in the ovary.
発生段階: Expressed in tissues undergoing reconstruction. Present in fetal tissues, especially in brain. Expression seems to decline with advanced development.
翻訳後: The precursor is cleaved by a furin endopeptidase (By similarity).
シーケンスの類似性: Belongs to the peptidase M10A family.
Contains 4 hemopexin repeats.
General information above from UniProt

MMP-16 代替名

MMP-16 関連研究

注意:すべての製品は、"研究目的のみに使用するものであり、診断または治療目的に使用するものではありません"