LDOC1 (タンパク質 | 抗体 | cDNA クローン | ELISA キット)

All LDOC1 reagents are produced in house and quality controlled, including 1 LDOC1 Antibody, 30 LDOC1 Gene, 1 LDOC1 qPCR. All LDOC1 reagents are ready to use.

LDOC1 Antibody (1)

LDOC1 cDNA Clone (30)

BC003104

クローニングベクター cDNA 製品

In lentiviral vector

NM_001260647.2

クローニングベクター cDNA 製品

In lentiviral vector

LDOC1 qPCR Primer (1)

LDOC1 関連の研究分野

LDOC1 の背景知識

LDOC1 was first identified as a gene encoding a leucine zipper protein whose expression was decreased in a series of pancreatic and gastric cancer cell lines. LDOC1 gene is a known regulator of nuclear factor mediated pathway to apoptosis through inhibition of nuclear factor kappa B (NF-kappaB). Upregulation of LDOC1 in HIBEC increases the expression of NF-kappaB, which may promote the activation of IL-2 and TNF-alpha secretion and inhibit cell apoptosis. The silencing of LDOC1 is a frequent event in cervical cancer and may be of interest as a molecular marker in cervical cancer.