Anti-Cytokeratin 5 / KRT5 Antibody

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Anti-Cytokeratin 5 / KRT5 Antibody (Rabbit Monoclonal 抗体) の製品情報

製品名
Anti-Cytokeratin 5 / KRT5 Antibody
検証済のアプリケーション
IHC-P
交差反応
Reacts with: Human
Predicted to React with: Mouse, Rat (Species predicted to react based on 100% sequence homology)
特異性
Human Cytokeratin 5 / KRT5
免疫原
A synthetic peptide corresponding to the center region of the human KRT5
調製
This antibody was obtained from a rabbit immunized with a synthetic peptide corresponding to the center region of the human KRT5.
ソース
Monoclonal Rabbit IgG Clone #104
精製
Protein A
緩衝液
0.2 μm filtered solution in PBS
標識物
Unconjugated
状態
Liquid
配送方法
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
保存条件
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-Cytokeratin 5 / KRT5 Antibody (Rabbit Monoclonal 抗体) 検証済のアプリケーション

アプリケーション 推奨希釈率/用量
IHC-P 1:100-1:500
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-Cytokeratin 5 / KRT5 Antibody (Rabbit Monoclonal 抗体) の画像

Immunochemical staining of human CK5 in human skin with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).
Immunochemical staining of human CK5 in human gastric cancer with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).
Immunochemical staining of human CK5 in human breast carcinoma with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).

Anti-Cytokeratin 5 / KRT5 Antibody: 別名

Anti-CK5 Antibody; Anti-DDD Antibody; Anti-DDD1 Antibody; Anti-EBS2 Antibody; Anti-K5 Antibody; Anti-KRT5A Antibody

Cytokeratin 5 / KRT5 背景情報

Keratin 5 is the major type II keratin of the basal cells of epidermis and of other stratified epithelia. With its type I partner, keratin 14, it constitutes a major fraction of the cytoskeleton of the basal cells. Epidermolysis bullosa simplex with mottled pigmentation (EBS-MP) is a rare dermatologic disorder of autosomal dominant inheritance with intraepidermal blistering after minor trauma, reticular hyperpigmentation unrelated to the blistering, nail dystrophy, and mild palmoplantar keratosis. Keratin 5 and keratin 14 are known to be essential for the basal keratinocyte cytoskeleton and are defective in several forms of epidermolysis bullosa simplex. Recently, a 71C-->T transition in the keratin 5 gene (KRT5) causing a P24L substitution was identified in some patients with EBS-MP.
氏名
keratin 5, type II
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