After search, choose a molecule or a kind of categories listed in the left to narrow down your filter. If you have any problems, please contact us!

クイック注文

Text Size:AAA

インフルエンザ A H9N2 (A/Duck/HongKong/448/78) Hemagglutinin / HA 蛋白質 (His タグ)

データシートレビュー関連製品プロトコル
H9N2 HA タンパク質製品情報
同意語:Hemagglutinin, HA
タンパク質構造:A DNA sequence encoding the Influenza A virus (A/Duck/HongKong/448/78(H9N2)) hemagglutinin (AAO46079.1) (Met1-Lys523), termed as HA, was expressed with a polyhistidine tag at the C-terminus.
:H9N2
発現宿主:Baculovirus-Insect Cells
フォーム & 配送:In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
H9N2 HA タンパク質 QC 試験
純度:> 95 % as determined by SDS-PAGE
生物活性:Measured by its ability to agglutinate guinea pig red blood cells.
HA titer is 0.02-0.1μg/mL for 1%GRBC
エンドトキシン:< 1.0 EU per μg protein as determined by the LAL method.
安定性:Samples are stable for up to twelve months from date of receipt at -70℃
予測される N ターミナル:Asp 19
分子質量:The recombinant hemagglutinin of Influenza A virus (A/Duck/HongKong/448/78(H9N2)) consists 516 amino acids and predicts a molecular mass of 58.2 kDa.
製剤:Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 10 % glycerol, pH 7.4.
1. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
2. Please contact us for any concerns or special requirements.
H9N2 HA タンパク質使用ガイド
保存:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
再構成:A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
H9N2 HA Protein SDS-PAGE
Influenza A H9N2 (A/Duck/HongKong/448/78) Hemagglutinin / HA Protein (His Tag)

HA 関連経路

    Other HA Recombinant Protein Products
    HA 背景

    The influenza viral Hemagglutinin (HA) protein is a homo trimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two functions. Firstly, it allows the recognition of target vertebrate cells, accomplished through the binding to these cells' sialic acid-containing receptors. Secondly, once bound it facilitates the entry of the viral genome into the target cells by causing the fusion of host endosomal membrane with the viral membrane.The influenza virus Hemagglutinin (HA) protein is translated in cells as a single protein, HA0, or hemagglutinin precursor protein. For viral activation, hemagglutinin precursor protein (HA0) must be cleaved by a trypsin-like serine endoprotease at a specific site, normally coded for by a single basic amino acid (usually arginine) between the HA1 and HA2 domains of the protein. After cleavage, the two disulfide-bonded protein domains produce the mature form of the protein subunits as a prerequisite for the conformational change necessary for fusion and hence viral infectivity.

    H9N2 HA 参考文献
  • White JM, Hoffman LR, Arevalo JH, et al. (1997). "Attachment and entry of influenza virus into host cells. Pivotal roles of hemagglutinin". In Chiu W, Burnett RM, Garcea RL. Structural Biology of Viruses.
  • Suzuki Y (March 2005). "Sialobiology of influenza: molecular mechanism of host range variation of influenza viruses". Biol. Pharm. Bull. 28 (3): 399–408.
  • Senne DA, Panigrahy B, Kawaoka Y, et al. (1996). "Survey of the hemagglutinin (HA) cleavage site sequence of H5 and H7 avian influenza viruses: amino acid sequence at the HA cleavage site as a marker of pathogenicity potential". Avian Dis. 40 (2): 425–37
  • Product nameProduct name
    Size / Price
    カタログ: 40003-V08B-50
    定価: 
    価格:      (You Save: )
    Contact Us
    画像
    • Influenza A H9N2 (A/Duck/HongKong/448/78) Hemagglutinin / HA Protein (His Tag)
      All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
      注意:すべての製品は、"研究目的のみに使用するものであり、診断または治療目的に使用するものではありません"