TIMP2 qPCR Primer Pairs, Human

Cat: HP100428
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TIMP2 qPCR Primer Pairs, Human General Information
Target Details
Species:
Human
Product Details
Oligo-Type:
qPCR Primers
Component:
1 vial of lyophilized qPCR primer mix (1 nmol each primer, sufficient for 200 numbers of 25 μl reactions).
QPCR Primer Description:
Verified forward and reverse primers for analyzing the quantitative expression of gene.
Application & Quality
Application:
SYBR® Green-based quantitative real-time PCR (qPCR).
Quality Control:
The primer mix has been verified to generate satisfactory qPCR data on Roche Applied-science LightCycler® 480 Ⅱ.
Storage & Shipping
Shipping:
Lyophilized qPCR primer mix is shipped at ambiente temperatura
Storage:
The lyophilized product is stable for one year from date of receipt when stored at -20℃. The suspended product is stable for six months from date of receipt when stored at -20℃.

***Sino biological qEASY qPCR primer pairs are used for SYBR Green-based real-time RT-PCR, The primers are designed by using SBI's proprietary primer design algorithm. Our primer collection covers the entire human genomes. It can be widely applied in the quantitative analysis of gene expression.***

Features and Advantages
Unique Primer Design
To avoid genomic DNA amplification, at least one primer is designed crosses the junction of exons according to the conserved region of a specific gene with all variants.
Strict Validation Process
Confirmed in positive organizations; screened the primer with high specificity and high sensitivity.
Uniform PCR conditions, Saving time and cost
~100% amplification curve, ensuring the accuracy of the RNA quantitative
TIMP2 qPCR Primer Pairs, Human Alternative Names
CSC-21K qPCR Primer Pairs, Human;DDC8 qPCR Primer Pairs, Human
TIMP2 Background Information

Tissue inhibitors of metalloproteinases (TIMP) family are natural inhibitors of the matrix metalloproteinases (MMPs), the zinc enzymes involved in extracellular matrix maintenance and remodeling. The TIMP family encompasses four members (TIMP1-4), and they inhibit most MMPs by forming non-covalent binary complex. TIMP2 is a 22 kDa non N-glycosylated protein expressed by a variety of cell types, and plays a unique role among TIMP family members owing to its functions to regulate cellular responses to growth factors. Findings establish an unexpected, MMP-independent mechanism for TIMP2 inhibition of endothelial cell proliferation in vitro and reveal an important component of the antiangiogenic effect of TIMP2 in vivo. TIMP-2 thus is critical to the maintenance of tissue homeostasis and is involved in the regulation of tumor microenvironment.

Full Name
TIMP metallopeptidase inhibitor 2
References
  • Stetler-Stevenson, W.G. et al., 1992, Matrix. Suppl.1: 299-306.
  • Stetler-Stevenson, W.G. et al., 2005, Trends. Mol. Med. 11: 97-103.
  • Seo, D.W. et al., 2003, Cell. 114: 171-180.
  • TIMP2 qPCR Primer Pairs, Mouse, Related Products

    Product Name Catalog#(PDF)
    TIMP2 cDNA ORF Clone in Cloning Vector, Mouse MG50941-G
    TIMP2 cDNA ORF Clone, Mouse, untagged MG50941-UT
    TIMP2 Lentiviral cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50941-ACGLN
    TIMP2 cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50941-ACG
    TIMP2 cDNA ORF Clone, Mouse, C-OFPSpark® tag MG50941-ACR
    TIMP2 cDNA ORF Clone, Mouse, C-DDK (Flag®) tag MG50941-CF
    TIMP2 cDNA ORF Clone, Mouse, N-DDK (Flag®) tag MG50941-NF
    TIMP2 cDNA ORF Clone, Mouse, C-His tag MG50941-CH
    TIMP2 cDNA ORF Clone, Mouse, N-His tag MG50941-NH
    TIMP2 cDNA ORF Clone, Mouse, C-HA tag MG50941-CY
    TIMP2 cDNA ORF Clone, Mouse, N-HA tag MG50941-NY
    TIMP2 cDNA ORF Clone, Mouse, C-Myc tag MG50941-CM
    TIMP2 cDNA ORF Clone, Mouse, N-Myc tag MG50941-NM

    TIMP2 qPCR Primer Pairs, Human, Related Products

    Product Name Catalog#(PDF)
    TIMP2 cDNA ORF Clone in Cloning Vector, Human HG10396-M
    TIMP2 cDNA ORF Clone, Human, untagged HG10396-UT
    TIMP2 Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag HG10396-ACGLN
    TIMP2 cDNA ORF Clone, Human, C-GFPSpark® tag HG10396-ACG
    TIMP2 cDNA ORF Clone, Human, C-OFPSpark® tag HG10396-ACR
    TIMP2 cDNA ORF Clone, Human, C-DDK (Flag®) tag HG10396-CF
    TIMP2 cDNA ORF Clone, Human, N-DDK (Flag®) tag HG10396-NF
    TIMP2 cDNA ORF Clone, Human, C-His tag HG10396-CH
    TIMP2 cDNA ORF Clone, Human, N-His tag HG10396-NH
    TIMP2 cDNA ORF Clone, Human, C-HA tag HG10396-CY
    TIMP2 cDNA ORF Clone, Human, N-HA tag HG10396-NY
    TIMP2 cDNA ORF Clone, Human, C-Myc tag HG10396-CM
    TIMP2 cDNA ORF Clone, Human, N-Myc tag HG10396-NM
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