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人々 ARHI / DIRAS3 Gene ORF cDNA clone expression plasmid

    データシートレビュー関連製品プロトコル
    人々 DIRAS3 cDNA クローン製品情報
    Gene_bank_ref_id:BC005362
    cDNA サイズ:690bp
    cDNA の説明:Full length Clone DNA of Homo sapiens DIRAS family, GTP-binding RAS-like 3.
    遺伝子の別名:ARHI, NOEY2, DIRAS3
    :Human
    ベクター:pCMV3-untagged
    Plasmid:
    制限サイト:
    タグ シーケンス:
    シーケンスの説明:
    Sequencing primers:T7(TAATACGACTCACTATAGGG) BGH(TAGAAGGCACAGTCGAGG)
    ( We provide with DIRAS3 qPCR primers for gene expression analysis, HP102889 )
    Promoter:Enhanced CMV mammalian cell promoter
    Application:Stable or Transient mammalian expression
    Antibiotic in E.coli:Ampicillin
    Antibiotic in mammalian cell:Hygromycin
    Shipping_carrier:Each tube contains lyophilized plasmid.
    保存:The lyophilized plasmid can be stored at room temperature for three months.
    Product nameProduct name
    背景

    ARHI, also known as DIRAS3, belongs to the small GTPase superfamily, Di-Ras family. ARHI gene is a novel tumor suppressor gene located on chromosome 1p31. Downregulation of ARHI expression has been detected in many types of cancer. ARHI is expressed in normal ovarian and breast epithelial cells but not in ovarian and breast cancers. As a suppressor, ARHI is not only an important factor in the pathogenesis of gastric cancer, but also a potential factor for tumor aggravation. ARHI expression in gastric cancer can be employed to indicate favorable prognosis for the disease.

    参考文献
  • Pei XH. et al., 2011, Cell Biol Int. 35 (10): 1019-24.
  • Lin D. et al., 2011, J Int Med Res. 39 (5): 1870-5.
  • Wang W. et al., 2012, Oncol Rep. 27 (6): 1953-9.
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