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人々 CSNK1A1/Casein Kinase 1, alpha 1 Gene ORF cDNA clone expression plasmid

データシートレビュー関連製品プロトコル
Human CSNK1A1 cDNA クローン製品情報
Gene_bank_ref_id:NM_001892.4
cDNA サイズ:1014bp
cDNA の説明:Full length Clone DNA of Homo sapiens casein kinase 1, alpha 1.
遺伝子の別名:CK1, HLCDGP1, PRO2975, CSNK1A1
:Human
ベクター:pCMV3-untagged
Plasmid:pCMV3-CSNK1A1
制限サイト:KpnI + XbaI (6.1kb + 1.01kb)
タグ シーケンス:
シーケンスの説明:Identical with the Gene Bank Ref. ID sequence.
Sequencing primers:T7(TAATACGACTCACTATAGGG) BGH(TAGAAGGCACAGTCGAGG)
Promoter:Enhanced CMV mammalian cell promoter
Application:Stable or Transient mammalian expression
Antibiotic in E.coli:Ampicilin
Antibiotic in mammalian cell:Hygromycin
Shipping_carrier:Each tube contains lyophilized plasmid.
保存:The lyophilized plasmid can be stored at room temperature for three months.
Human CSNK1A1 Gene Plasmid Map
Human CSNK1A1 Gene cDNA Clone (full-length ORF Clone), expression ready, untagged
人々 CSNK1A1/Casein Kinase 1, alpha 1 Gene ORF cDNA clone expression plasmid on other vectors
人々 CSNK1A1/Casein Kinase 1, alpha 1 Gene ORF cDNA clone expression plasmid, C-GFPSpark タグHG10668-ACGJPY54410
人々 CSNK1A1/Casein Kinase 1, alpha 1 Gene ORF cDNA clone expression plasmid, C-OFPSpark タグHG10668-ACRJPY54410
人々 CSNK1A1/Casein Kinase 1, alpha 1 Gene ORF cDNA clone expression plasmid, N-GFPSpark タグHG10668-ANGJPY54410
人々 CSNK1A1/Casein Kinase 1, alpha 1 Gene ORF cDNA clone expression plasmid, N-OFPSpark タグHG10668-ANRJPY54410
人々 CSNK1A1/Casein Kinase 1, alpha 1 Gene ORF cDNA clone expression plasmid, C-Flag タグHG10668-CFJPY47150
人々 CSNK1A1/Casein Kinase 1, alpha 1 Gene ORF cDNA clone expression plasmid, C-His タグHG10668-CHJPY47150
人々 CSNK1A1/Casein Kinase 1, alpha 1 Gene ORF cDNA clone expression plasmid, C-Myc タグHG10668-CMJPY47150
人々 CSNK1A1/Casein Kinase 1, alpha 1 Gene ORF cDNA clone expression plasmid, C-HA タグHG10668-CYJPY47150
人々 CSNK1A1/Casein Kinase 1, alpha 1 Gene ORF cDNA clone in cloning vectorHG10668-MJPY18140
人々 CSNK1A1/Casein Kinase 1, alpha 1 Gene ORF cDNA clone expression plasmid, C-Flag タグHG10668-M-FJPY47150
人々 CSNK1A1/Casein Kinase 1, alpha 1 Gene ORF cDNA clone expression plasmid, N-Flag タグHG10668-NFJPY47150
人々 CSNK1A1/Casein Kinase 1, alpha 1 Gene ORF cDNA clone expression plasmid, N-His タグHG10668-NHJPY47150
人々 CSNK1A1/Casein Kinase 1, alpha 1 Gene ORF cDNA clone expression plasmid, N-Myc タグHG10668-NMJPY47150
人々 CSNK1A1/Casein Kinase 1, alpha 1 Gene ORF cDNA clone expression plasmid, N-HA タグHG10668-NYJPY47150
人々 CSNK1A1/Casein Kinase 1, alpha 1 Gene ORF cDNA clone expression plasmidHG10668-UTJPY47150
 発現ベクターの詳細情報
Product nameProduct name
背景

Casein kinase I isoform alpha, also known as CKI-alpha, CK1 and CSNK1A1, is a cytoplasm protein which belongs to the protein kinase superfamily, CK1 Ser/Thr protein kinase family and casein kinase I subfamily. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. High expression of CSNK2A1, or concomitantly high expression of CSNK2A1, are independent prognostic factors of poor survival in NSCLC patients. CSNK2A1 are useful prognosis markers in non-small cell lung cancer (NSCLC) patients after complete resection, independent of lymph node metastasis status. CSNK1A1 can phosphorylate a large number of proteins. It participates in Wnt signaling. It phosphorylates CTNNB1 at 'Ser-45'. CSNK1A1 may play a role in segregating chromosomes during mitosis.

参考文献
  • Dubois, et al.,2002, FEBS Lett. (Netherlands) 517 (1-3): 167-71. 
  • Dubois, T et al.,2001, J. Biol. Chem.(United States) 276 (22): 18757-64.
  • Zhang, Yi et al., 2002, J. Biol. Chem. 277(20): 17706-12.
  • Wang,Z. et al., 2010, Med Sci Monit.16 (8):CR357-64.
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    カタログ: HG10668-UT
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    • Human CSNK1A1 Gene cDNA Clone (full-length ORF Clone), expression ready, untagged
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