All Clusterin reagents are produced in house and quality controlled, including 16 Clusterin Antibody, 67 Clusterin Gene, 1 Clusterin IPKit, 2 Clusterin Lysate, 2 Clusterin Protein, 2 Clusterin qPCR. All Clusterin reagents are ready to use.
Recombinant Clusterin proteins are expressed by HEK293 Cells with fusion tags as C-His.
Clusterinantibodies are validated with different applications, which are ELISA, FCM, WB, ICC/IF, IF, IP, IHC-P.
ClusterincDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each Clusterin of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
Clusterin, also known as complement-associated protein SP-40, Complement cytolysis inhibitor, Apolipoprotein J, Testosterone-repressed prostate message 2, Aging-associated gene 4 protein, CLU and APOJ, is a secreted protein which belongs to the clusterin family. Clusterin/Apolipoprotein J/Apo-J is an enigmatic glycoprotein with a nearly ubiquitous tissue distribution and an apparent involvement in biological processes ranging from mammary gland involution to neurodegeneration in Alzheimer's disease. Its major form, a heterodimer, is secreted and present in physiological fluids, but truncated forms targeted to the nucleus have also been identified. Clusterin/Apolipoprotein J/Apo-J is a widely distributed glycoprotein with a wide range of biologic properties. A prominent and defining feature of clusterin is its marked induction in such disease states as glomerulonephritis, cystic renal disease, renal tubular injury, neurodegenerative conditions, atherosclerosis, and myocardial infarction. Upregulation of clusterin mRNA and protein levels detected in diverse disease states and in in vitro systems have led to suggestions that it functions in membrane lipid recycling, in apoptotic cell death, and as a stress-induced secreted chaperone protein, amongst others.