CLPX: CLPX Protein | CLPX Antibody

CLPX Gene family

CLPX Protein

CLPX protein function

ATP-dependent specificity component of the Clp protease complex. Hydrolyzes ATP. Targets specific substrates for degradation by the Clp complex (PubMed:11923310, PubMed:22710082). Can perform chaperone functions in the absence of CLPP. Enhances the DNA-binding activity of TFAM and is required for maintaining a normal mitochondrial nucleoid structure (PubMed:22841477). ATP-dependent unfoldase that stimulates the incorporation of the pyridoxal phosphate cofactor into 5-aminolevulinate synthase, thereby activating 5-aminolevulinate (ALA) synthesis, the first step in heme biosynthesis. Important for efficient erythropoiesis through upregulation of heme biosynthesis (PubMed:25957689).

CLPX protein expression

Tissue specificity

Higher expression in skeletal muscle and heart and to a lesser extent in liver, brain, placenta, lung, kidney and pancreas.

CLPX protein sequence

This sequence information is just for reference only.From Uniport

  • Length
    633.00
  • Mass (Da)
    69.00

CLPX Antibody

There are 1 CLPX antibodies which are validated in multiple tissues with various applications, including IHC-P. There are 1 CLPX antibody for IHC-P. Among all these CLPX antibodies, there are 1 anti-CLPX rabbit polyclonal antibodies . All the CLPX anbodies are produced in house and all are in stock. CLPX antibody customerized service is available.

CLPX Gene

CLPX cDNA / gene is a gene with protein product which located on 15q22.31. The CLPX gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, C.elegans, S.cerevisiae, K.lactis, M.oryzae, and N.crassa. 241 organisms have orthologs with human gene CLPX.