CHTF18: CHTF18 Protein | CHTF18 Antibody

CHTF18 Gene family

CHTF18 Protein

CHTF18 protein function

Chromosome cohesion factor involved in sister chromatid cohesion and fidelity of chromosome transmission. Component of one of the cell nuclear antigen loader complexes, CTF18-replication factor C (CTF18-RFC), which consists of CTF18, CTF8, DCC1, RFC2, RFC3, RFC4 and RFC5. The CTF18-RFC complex binds to single-stranded and primed DNAs and has weak ATPase activity that is stimulated by the presence of primed DNA, replication protein A (RPA) and by proliferating cell nuclear antigen (PCNA). The CTF18-RFC complex catalyzes the ATP-dependent loading of PCNA onto primed and gapped DNA. It also interacts with and stimulates DNA polymerase POLH.

CHTF18 protein sequence

This sequence information is just for reference only.From Uniport

  • Length
  • Mass (Da)

CHTF18 Gene

CHTF18 cDNA / gene is a gene with protein product which located on 16p13.3. The CHTF18 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, A.thaliana, rice, and frog. 236 organisms have orthologs with human gene CHTF18.