CFHR1 (タンパク質 | 抗体 | cDNA クローン | ELISA キット)

All CFHR1 reagents are produced in house and quality controlled, including 2 CFHR1 Antibody, 14 CFHR1 Gene, 1 CFHR1 Lysate, 1 CFHR1 Protein. All CFHR1 reagents are ready to use.

CFHR1 Protein (1)

CFHR1 Antibody (2)

CFHR1 cDNA Clone (14)

NM_002113.2

In expression vector

NM_015780.2

クローニングベクター cDNA 製品

In lentiviral vector

CFHR1 Lysate (1)

CFHR1 関連の研究分野

CFHR1 の背景知識

CFHR1 is a secreted protein belonging to the complement factor H protein family.The human complement factor H protein family consists of the complement and immune regulators factor H, the factor H-like protein 1(FHL-1) and five factor H-related proteins (CFHR-1 to -5). Members of the H-related protein family are exclusively composed of individually folded protein domains, termed short consensus repeats (SCRs) or complement control modules. CFHR1 binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. CFHR1 might be involved in complement regulation. It can associate with lipoproteins and may play a role in lipid metabolism.

CFHR1 の参考文献

  • Martnez-Barrica, et al. (2012) Relevance of complement factor H-related 1 (CFHR1) genotypes in age-related macular degeneration. Invest Ophthalmol Vis Sci. 53(3):1087-94.
  • Leban N, et al. (2012) Factor H and CFHR1 polymorphisms associated with atypical Haemolytic Uraemic Syndrome (aHUS) are differently expressed in Tunisian and in Caucasian populations. Int J Immunogenet. 39(2):110-3.
  • Kubista KE, et al. (2011) Copy number variation in the complement factor H-related genes and age-related macular degeneration. Int J Immunogenet. Mol Vis. 17:2080-92.