CD3G (Protein | Antibody | cDNA Clone | ELISA Kit)

All CD3G reagents are produced in house and quality controlled, including 1 CD3G Antibody, 52 CD3G Gene, 3 CD3G qPCR. All CD3G reagents are ready to use.

CD3G Antibody (1)

CD3G cDNA Clone (52)

NM_000073.2
NM_009850.2
NM_001077646.1
XM_001093643.2

CD3G Background

CD3G gene encodes CD3-gamma polypeptide, which together with CD3-epsilon, -delta, and -zeta, and the TCR alpha/beta and gamma/delta heterodimers, forms the TCR-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The CD3 gamma chain has long been considered to mediate targeting to lysosomes for degradation. Defects in this gene are associated with T cell immunodeficiency. Further, it has been proposed as one of the important candidate genes for cancer development due to its pivotal roles in TCR signaling pathway.Immune CheckpointImmunotherapyCancer ImmunotherapyTargeted Therapy

CD3G References

  • Jiang L, Xu J, Ni J, et al. A Functional Insertion/Deletion Polymorphism in the Proximal Promoter of CD3G Is Associated with Susceptibility for Hepatocellular Carcinoma in Chinese Population. DNA and Cell Biology.