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CCL16 / HCC-4 / NCC4  Protein, Antibody, ELISA Kit, cDNA Clone

発現宿主: Yeast  
10491-H08Y-50
10491-H08Y-20
50 µg 
20 µg 
Add to Cart
  • Slide 1
発現宿主: E. coli  
10491-H07E-50
10491-H07E-20
50 µg 
20 µg 
Add to Cart
  • Slide 1

CCL16 / HCC-4 / NCC4 Related Area

CCL16 / HCC-4 / NCC4 関連経路

    CCL16 / HCC-4 / NCC4 サマリー & タンパク質情報

    CCL16 / HCC-4 / NCC4 背景

    細胞内位置: Secreted.
    組織特異性: Mainly expressed in liver, also found in spleen and thymus. Highly expressed in LPS- and IFN-gamma-activated monocytes, weakly in some lymphocytes, including natural killer cells, gamma-delta T-cells, and some T-cell clones.
    誘導: By IL10/interleukin-10.
    シーケンスの類似性: Belongs to the intercrine beta (chemokine CC) family. {ECO:0000305}.
    General information above from UniProt

    CCL16, a chemokine poorly characterized at the functional level. Human CCL16 is a member of the CC family, and its gene maps to human chromosome 17q. In the mouse, only a pseudogene has been identified to date. CCL16 is a functional ligand for CCR1, CCR2, CCR5, and CCR8. Recombinant CCL16 demonstrated chemotactic activity on human monocytes and lymphocytes. Based on the ability of human chemokines to exert activity on and bind to murine receptors, the TSA mouse adenocarcinoma cell line was transfected with human CCL16 cDNA and, in comparison with other cytokines, was shown to be the faster inducer of systemic immune response due to massive, prompt infiltration of leukocytes.

    Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

    CCL16 / HCC-4 / NCC4 代替名

    chemokine (C-C motif) ligand 16,CCL16,CKb12,HCC-4,ILINCK,LCC-1,LEC,LMC,Mtn-1,NCC-4,NCC4,SCYA16,SCYL4,C-C motif chemokine 16,IL-10-inducible chemokine,chemokine CC-4,chemokine LEC,liver CC chemokine-1,liver-expressed chemokine,lymphocyte and monocyte chemoattractant,monotactin-1,new CC chemokine 4,small inducible cytokine subfamily A (Cys-Cys), member 16,small-inducible cytokine A16, [human]

    CCL16 / HCC-4 / NCC4 関連研究

  • Guiducci C, Di Carlo E, Parenza M, et al. Intralesional injection of adenovirus encoding CC chemokine ligand 16 inhibits mammary tumor growth and prevents metastatic-induced death after surgical removal of the treated primary tumor[J]. The Journal of Immunology, 2004, 172(7): 4026-4036.
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