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CAMKV  タンパク質

All CAMKV Reagents

発現宿主: Baculovirus-Insect Cells  
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12243-H20B-20
12243-H20B-50
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50 µg 
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CAMKV 関連経路

CAMKV サマリー & タンパク質情報

CAMKV 背景

遺伝子の概要: OMIM - description for CAMKV:
General information above from NCBI
補因子: Calcium (By similarity).
サブユニット構造: Interacts with calmodulin, in the presence of calcium (By similarity).
ドメイン: The protein kinase domain is predicted to be catalytically inactive.
細胞内位置: Cell membrane; Peripheral membrane protein (By similarity). Cytoplasmic vesicle membrane; Peripheral membrane protein (By similarity). Note=Predominantly observed in association with the plasma membrane of soma and in neurites, both axons and dendrites. May be associated with vesicular structures (By similarity).
シーケンスの類似性: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
Contains 1 protein kinase domain.C
General information above from UniProt

CaM kinase-like vesicle-associated protein, also known as CAMKV, is a peripheral membrane protein and Cytoplasmic vesicle membrane protein which belongs to the protein kinase superfamily and CAMK Ser/Thr protein kinase family. CAMKV contains one protein kinase domain. It is predominantly observed in association with the plasma membrane of soma and in neurites, both axons and dendrites. CAMKV may be associated with vesicular structures. It does not appear to have detectable kinase activity.

Protein kinases are a group of enzymes that move a phosphate group onto proteins, in a process called phosphorylation. Protein kinases function as an on/off switch for many cellular processes, including metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. They also function in embryonic development, physiological responses, and in the nervous and immune system. Abnormal phosphorylation causes many human diseases, including cancer, and drugs that affect phosphorylation can treat those diseases. The protein kinase domain is a structurally conserved protein domain containing the catalytic function of protein kinases. Protein kinases play a role in a mulititude of cellular processes, including division, proliferation, apoptosis, and differentiation. Phosphorylation usually results in a functional change of the target protein by changing enzyme activity, cellular location, or association with other proteins.

CAMKV 代替名

1G5,VACAMKL, [homo-sapiens]
1G5,MGC8407,CAMKV,VACAMKL, [human]
1G5,BB074618,BC017634,Camkv,MGC118008,MGC28873, [mouse]
1G5,BB074618,BC017634, [mus-musculus]

CAMKV 関連研究

  • Hunter T, et al.,1988, Science. 241 (4861): 42-51.
  • Wiemann S., et al., 2001, Genome Res. 11:422-435.
  • G. Manning, et al., 2002, Science 6. 298:1912-1934.
  • Manning G, et al.,2002, Science. 298 (5600): 1912-34.
  • Ota T., et al., 2004, Nat. Genet. 36:40-45.
  • 注意:すべての製品は、"研究目的のみに使用するものであり、診断または治療目的に使用するものではありません"