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C1R  Protein, Antibody, ELISA Kit, cDNA Clone

C1R Related Area

C1R サマリー & タンパク質情報

C1R 背景

触媒活性: Selective cleavage of Lys(or Arg)-|-Ile bond in complement subcomponent C1s to form the active form of C1s (EC 3.4.21.42).
サブユニット構造: C1 is a calcium-dependent trimolecular complex of C1q, C1r and C1s in the molar ration of 1:2:2. C1r is a dimer of identical chains, each of which is activated by cleavage into two chains, A and B, connected by disulfide bonds.
翻訳後: The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains. {ECO:0000269|PubMed:2820791}.
シーケンスの類似性: Belongs to the peptidase S1 family. {ECO:0000255|PROSITE-ProRule:PRU00274}.; Contains 2 CUB domains. {ECO:0000255|PROSITE-ProRule:PRU00059}.; Contains 1 EGF-like domain. {ECO:0000305}.; Contains 1 peptidase S1 domain. {ECO:0000255|PROSITE-ProRule:PRU00274}.; Contains 2 Sushi (CCP/SCR) domains. {ECO:0000255|PROSITE-ProRule:PRU00302}.
General information above from UniProt

C1R 代替名

C1R 関連研究

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