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A transferase/B transferase  ELISA Pair Set

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A transferase/B transferase

A transferase/B transferase ELISA Pair Set

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    A transferase/B transferase サマリー & タンパク質情報

    A transferase/B transferase 背景

    触媒活性: UDP-N-acetyl-alpha-beta-D-galactosamine + glycoprotein-alpha-L-fucosyl-(1->2)-D-galactose = UDP + glycoprotein-N-acetyl-alpha-D-galactosaminyl-(1->3)-(alpha-L-fucosyl-(1->2))-beta-D-galactose.; UDP-alpha-D-galactose + alpha-L-fucosyl-(1->2)-D-galactosyl-R = UDP + alpha-D-galactosyl-(1->3)-(alpha-L-fucosyl-(1->2))-D-galactosyl-R.
    補因子: Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000269|PubMed:17259183}; ; Note=Binds 1 Mn(2+) ion per subunit. {ECO:0000269|PubMed:17259183};
    ドメイン: The conserved DXD motif is involved in cofactor binding. The manganese ion interacts with the beta-phosphate group of UDP and may also have a role in catalysis.
    細胞内位置: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Secreted. Note=Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid.
    翻訳後: The soluble form derives from the membrane form by proteolytic processing.
    シーケンスの類似性: Belongs to the glycosyltransferase 6 family. {ECO:0000305}.
    General information above from UniProt

    A transferase/B transferase 代替名

    GTB,NAGAT,A3GALNT,A3GALT1, [homo-sapiens]
    NAGAT, [mus-musculus]

    A transferase/B transferase 関連研究

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