BCRP / ABCG2 cDNA ORF Clone in Cloning Vector, Rhesus

Price:
Size:
Number:

BCRP / ABCG2 cDNA ORF Clone in Cloning Vector, Rhesus: 製品情報

遺伝子
Rhesus
NCBI 参考シーケンス番号
遺伝子の長さ
1965 bp
シーケンスの特徴
Identical with the Gene Bank Ref. ID sequence except for the point mutations: 166C/G(R56G), 1840G/A(A614Y). Please check the sequence information before order.
製品の特徴
Full length Clone DNA of Rhesus ATP-binding cassette, sub-family G (WHITE), member 2.
プラスミド
ベクター
シークエンシングプライマー
SP6 and T7 or M13-47 and RV-M
品質管理
The plasmid is confirmed by full-length sequencing.
スクリーニング
細菌スクリーニング抵抗力
Ampicillin
保存 & 配送
配送方法
Each tube contains lyophilized plasmid.
保存条件
The lyophilized plasmid can be stored at ambient temperature for three months.

BCRP / ABCG2 cDNA ORF ヌクレオチド配列およびアミノ酸配列に関する情報

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

BCRP / ABCG2 背景情報

ATP-binding cassette subfamily G member 2 (ABCG2), a member of the ABC transporter superfamily proteins. the expression of ABCG2 is related to tumorigenic cancer stem cells (CSC) in several cancers, mediates multidrug resistance (MDR) by transporting substrate anticancer drugs out of cancer cells and decreasing their intracellular accumulation. ABCB1 and ABCG2 are efflux transporters which have a major impact on the pharmacological behavior of numerous drugs. They are expressed in the intestine, liver, kidney, BBB and placenta. It has become evident that ABCB1 and ABCG2 modify the pharmaco/toxicokinetics in the placenta and fetus and may consequently affect the outcome of pregnancy.
完全な名称
ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
カートに追加しました カートに追加しませんでした カートを更新しています。少々お待ちください