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Aminoadipate aminotransferase  タンパク質

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Aminoadipate aminotransferase サマリー & タンパク質情報

Aminoadipate aminotransferase 背景

触媒活性: L-kynurenine + 2-oxoglutarate = 4-(2- aminophenyl)-2,4-dioxobutanoate + L-glutamate.
L-2-aminoadipate + 2-oxoglutarate = 2- oxoadipate + L-glutamate.
補因子: Pyridoxal phosphate.
酵素調節: Kynurenine transaminase activity is competitively inhibited by aminoadipate, asparagine, glutamate, histidine, cysteine, lysine, 3-hydroxy-kynurenine and phenylalanine.
サブユニット構造: Homodimer.
細胞内位置: Mitochondrion (Potential).
組織特異性: Higher expression in the liver. Also found in heart, brain, kidney, pancreas, prostate, testis and ovary.
シーケンスの類似性: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.C
General information above from UniProt

Aminoadipate aminotransferase 代替名

KAT2,KATII, [homo-sapiens]
Aadt,Kat2,KATII,mKat-2,AI875679, [mus-musculus]

Aminoadipate aminotransferase 関連研究