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4E-BP1/EIF4EBP1

4E-BP1/EIF4EBP1 タンパク質 & 抗体

Entrez Gene Summary for 4E-BP1/EIF4EBP1の Entrez Gene サマリー


This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

OMIM-Description for 4E-BP1/EIF4EBP1OMIM-説明


inhibited the mTORC1 (601231) pathway in cells lacking EIF4EBP1, EIF4EBP2 (602224), and EIF4EBP3 (603483) and analyzed the effects on cell size, cell proliferation, and cell cycle progression. Although the EIF4EBPs had no effect on cell size, they inhibited cell proliferation by selectively inhibiting the translation of mRNAs that encode proliferation-promoting proteins and proteins involved in cell cycle progression. Thus, Dowling et al. (2010) concluded that control of cell size and cell cycle progression appear to be independent in mammalian cells, whereas in lower eukaryotes, EIF4E binding proteins influence both cell growth and proliferation.

.zh=のウィキペディア サマリー 4E-BP1/EIF4EBP1


EIF4EBP1

4E-BP1/EIF4EBP1 代替名

4E-BP1/EIF4EBP1 Related Products

4E-BP1/EIF4EBP1 Proteins

Product nameProduct name
人々 4E-BP1 / EIF4EBP1 蛋白質 (His タグ)

4E-BP1/EIF4EBP1 Antibodies

Product nameProduct name
4E-BP1 / EIF4EBP1 抗体, ウサギモノクローナル抗体4E-BP1 / EIF4EBP1 抗体, マウスモノクローナル抗体4E-BP1 / EIF4EBP1 抗体, マウスモノクローナル抗体4E-BP1 / EIF4EBP1 抗体, ウサギモノクローナル抗体4E-BP1 / EIF4EBP1 抗体 (FITC), マウスモノクローナル抗体4E-BP1 / EIF4EBP1 抗体 (PE), マウスモノクローナル抗体4E-BP1 / EIF4EBP1 抗体, ウサギポリクローナル抗体4E-BP1 / EIF4EBP1 抗体, ウサギモノクローナル抗体4E-BP1 / EIF4EBP1 抗体, ウサギポリクローナル抗体, Antigen Affinity Purified

4E-BP1/EIF4EBP1 cDNA Clones

Product nameProduct name
人々 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, N-GFPSpark タグ人々 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, N-His タグマウス 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, N-Myc タグマウス 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, N-His タグ人々 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, C-GFPSpark タグ人々 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, C-Myc タグ人々 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, N-Flag タグマウス 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, C-OFPSpark タグマウス 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, N-OFPSpark タグマウス 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, N-GFPSpark タグ人々 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, N-HA タグ人々 4E-BP1/EIF4EBP1 Gene ORF cDNA clone in cloning vector人々 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, C-HA タグ人々 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, C-OFPSpark タグ人々 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, N-OFPSpark タグマウス 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, N-HA タグマウス 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, C-Myc タグ人々 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, C-His タグ人々 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmidRat 4E-BP1/EIF4EBP1 Gene ORF cDNA clone in cloning vectorマウス 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, C-HA タグマウス 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, C-His タグマウス 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, N-Flag タグマウス 4E-BP1/EIF4EBP1 Gene ORF cDNA clone in cloning vector人々 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, C-Flag タグマウス 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, C-Flag タグマウス 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmidマウス 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, C-GFPSpark タグ人々 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, N-Myc タグ

4E-BP1/EIF4EBP1 ELISA

Product nameProduct name
注意:すべての製品は、"研究目的のみに使用するものであり、診断または治療目的に使用するものではありません"