Anti-4-1BBL Antibody

Cat: 80166-RP01

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All 4-1BBL Reagents

Anti-4-1BBL Antibody (Rabbit Polyclonal antibody) General Information

Product name
Anti-4-1BBL Antibody
Species reactivity
Reacts with: Rat
Rat 4-1BBL
Recombinant Rat 4-1BBL / CD137L protein (Catalog#80166-R07H)
Produced in rabbits immunized with purified, recombinant Rat 4-1BBL / CD137L (Catalog#80166-R07H; Q80WE6; Pro106-Gly308). Total IgG was purified by Protein A affinity chromatography.
Polyclonal Rabbit IgG
Protein A
0.2 μm filtered solution in PBS
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-4-1BBL Antibody (Rabbit Polyclonal antibody) Validated Applications

Application Dilution Notes
ELISA 1:1000-1:2000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

4-1BBL Background Information

4-1BBL is the high affinity ligand of 4-1BB, also known as CD137L or TNFSF9. It is shown to be a type II surface glycoprotein belonging to the TNF superfamily. Expression of 4-1BBL is restricted to APCs, such as dendritic cells, macrophages, and activated B cells. Members of the TNF-TNF receptor superfamily have been shown to play critical roles in regulating cellular activation, differentiation and apoptosis. Several studies have reported that 4-1BBL/4-1BB interaction provided a co-stimulatory signal to T cells, and increased T cell proliferation and cytokines production. In additon, 4-1BBL is involved in cancers, infectious diseases and autoimmune diseases.Immune Checkpoint
Immune Checkpoint Detection: Antibodies   Immune Checkpoint Detection: ELISA Antibodies   Immune Checkpoint Detection: ICC Antibodies   Immune Checkpoint Detection: FCM Antibodies
Immune Checkpoint Targets   Co-stimulatory Immune Checkpoint Targets Immunotherapy   Cancer Immunotherapy   Targeted Therapy
Full Name
tumor necrosis factor (ligand) superfamily, member 9
  • Cheung CT, (2007) Neutralizing anti-4-1BBL treatment improves cardiac function in viral myocarditis. Lab Invest. 87(7): 651-61.
  • Wang C, et al. (2009) Immune regulation by 4-1BB and 4-1BBL: complexities and challenges. Immunol Rev. 229(1): 192-215.
  • Habib-Agahi M, et al. (2009) 4-1BBL costimulation retrieves CD28 expression in activated T cells. Cell Immunol. 256(1-2): 39-46.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-4-1BBL Antibody Rabbit Polyclonal ELISA 80166-T16
    Anti-4-1BBL Antibody Rabbit Polyclonal ELISA 50067-RP02
    Anti-4-1BBL Antibody Rabbit Monoclonal ELISA,FCM,ICC/IF,IF 50067-R014
    Anti-4-1BBL Antibody (PerCP) Rabbit Monoclonal FCM 50067-R014-C
    Anti-4-1BBL Antibody Rabbit Polyclonal ELISA 50067-RP01
    Anti-4-1BBL Antibody (APC) Rabbit Monoclonal FCM 50067-R014-A
    Anti-4-1BBL Antibody (FITC) Rabbit Monoclonal FCM 50067-R014-F
    Anti-4-1BBL Antibody (PE) Rabbit Monoclonal FCM 50067-R014-P
    Anti-4-1BBL Antibody Rabbit Polyclonal ELISA 50067-T16
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