クイック注文

14-3-3 phospho-serine-phospho-threonine binding proteins

无标题文档

14-3-3 proteins: 14-3-3 proteins are a family of conserved regulatory molecules that are expressed in all eukaryotic cells. 14-3-3 proteins have the ability to bind a multitude of functionally diverse signaling proteins, including kinases, phosphatases, and transmembrane receptors. More than 200 signaling proteins have been reported as 14-3-3 ligands.The name 14-3-3 refers to the particular elution and migration pattern of these proteins on DEAE -cellulose chromatography and starch-gel electrophoresis. The 14-3-3 proteins eluted in the 14th fraction of bovine brain homogenate and were found on positions 3.3 of subsequent electrophoresis by Moore and Perez (1967).Elevated amounts of 14-3-3 proteins are found in the cerebrospinal fluid of patients with Creutzfeldt-Jakob disease. [Source: Wikipedia]

14-3-3 phospho-serine/phospho-threonine binding proteins members:
Approved Symbol Approved Name Previous Symbols Synonyms Chromosome Accession Numbers RefSeq IDs Gene family description
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta YWHAA 20q13.12 X57346 NM_003404 14-3-3 phospho-serine/phospho-threonine binding proteins
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon FLJ45465 17p13.3 U54778 NM_006761 14-3-3 phospho-serine/phospho-threonine binding proteins
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma PPP1R170 7q11.23 AF142498 NM_012479 14-3-3 phospho-serine/phospho-threonine binding proteins
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta YWHA1 22q12.3 X78138 NM_003405 14-3-3 phospho-serine/phospho-threonine binding proteins
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta HS1, 14-3-3 2p25.1 AF070556 NM_006826 14-3-3 phospho-serine/phospho-threonine binding proteins
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta YWHAD KCIP-1, 14-3-3-zeta 8q22.3 U28964 NM_145690 14-3-3 phospho-serine/phospho-threonine binding proteins
SFN stratifin YWHAS 1p36.11 BC023552 NM_006142 14-3-3 phospho-serine/phospho-threonine binding proteins
注意:すべての製品は、"研究目的のみに使用するものであり、診断または治療目的に使用するものではありません"